Most people who suffer from constipation manage a type known as functional or idiopathic constipation. This type of constipation is so called because the underlying cause is not identifiable, yet the condition can be easy diagnosed due to the symptoms. Treatment at first consists of increased dietary fiber. If this is ineffective, patients are recommended to try a laxative.
Generally the opinion among the scientist and researcher population is that using laxative constipation treatments properly is safe. But as constipation is occasionally a chronic condition that necessitates use of laxatives over long periods, suspicions about unintended side-effects and health issues have arisen. One problem is the development of myths regarding this line of medication.
The incorrect or at least poorly conceived myths regarding laxative use can be divided into three kinds. The first kind concerns the idea that using laxatives causes nerves to become damaged in the colonic tract. THe second kind is related to the idea that laxatives are carcinogenic or mutagenic agents which give rise to cancer. THe third kind is about the idea of laxative "intolerance", i.e. the efficacy wears off over time.
On the topic of the first misconception, reports about nerve damage came up first in a survey of patients who were using laxative constipation treatments. Colonoscopy showed discoloration in their intestinal lining, and some were diagnosed with damage to the nerves. But the correlative link was never made definitive. Many criticized the findings by pointing out in general patients with constipation had more chance of nerve damage, regardless of laxative use or not.
With respect to the second, reports linking laxatives to cancer were suggested by experimentation on animals. Rats fed extreme doses of anthraquinones had higher mutations in cells, leading to cancer-like problems. But the studies were not easily translatable to the human context because the doses were very non-realistic. Similar studies with extreme concentrations of aspartame sweetener and peanut oils show a cancer link, but are rarely relevant for realistic human consumption.
Regarding the third, it seems that anecdotes from patients who were seeing decreased efficacy gave rise to the belief of laxative intolerance. However, studies both in rats and in paraplegic patients who had been on laxatives for as long as 34 years showed that the efficacy of laxatives remained more or less undiminished over these long times.
It would seem that laxatives should not be discounted for their great utility against constipation because of these misconceptions. Patients should continue to research for themselves and ally with their doctors to understand the evidence concerning laxative efficacy.
Generally the opinion among the scientist and researcher population is that using laxative constipation treatments properly is safe. But as constipation is occasionally a chronic condition that necessitates use of laxatives over long periods, suspicions about unintended side-effects and health issues have arisen. One problem is the development of myths regarding this line of medication.
The incorrect or at least poorly conceived myths regarding laxative use can be divided into three kinds. The first kind concerns the idea that using laxatives causes nerves to become damaged in the colonic tract. THe second kind is related to the idea that laxatives are carcinogenic or mutagenic agents which give rise to cancer. THe third kind is about the idea of laxative "intolerance", i.e. the efficacy wears off over time.
On the topic of the first misconception, reports about nerve damage came up first in a survey of patients who were using laxative constipation treatments. Colonoscopy showed discoloration in their intestinal lining, and some were diagnosed with damage to the nerves. But the correlative link was never made definitive. Many criticized the findings by pointing out in general patients with constipation had more chance of nerve damage, regardless of laxative use or not.
With respect to the second, reports linking laxatives to cancer were suggested by experimentation on animals. Rats fed extreme doses of anthraquinones had higher mutations in cells, leading to cancer-like problems. But the studies were not easily translatable to the human context because the doses were very non-realistic. Similar studies with extreme concentrations of aspartame sweetener and peanut oils show a cancer link, but are rarely relevant for realistic human consumption.
Regarding the third, it seems that anecdotes from patients who were seeing decreased efficacy gave rise to the belief of laxative intolerance. However, studies both in rats and in paraplegic patients who had been on laxatives for as long as 34 years showed that the efficacy of laxatives remained more or less undiminished over these long times.
It would seem that laxatives should not be discounted for their great utility against constipation because of these misconceptions. Patients should continue to research for themselves and ally with their doctors to understand the evidence concerning laxative efficacy.
About the Author:
Additional resources supplied for constipation remedies can be located here. Discover the newest information and writings in regards to amitiza for constipation.
No comments:
Post a Comment