Thursday, June 17, 2010

If You Are Prescribed Florinef, Request It From An Online Pharmacy

By Kristofer Marchall

Doctor Thomas Addison, a British doctor in the 19th century, is credited with fist describing a disease of the supra renal capsule. Because the symptoms of this disease manifest themselves in so many different ways, it was some time before the connection of the symptoms to the cause was identified. Fortunately, with the development of such drugs as Florinef, the disease is quite treatable.

Unlike the disease named for the first physician to describe its symptoms in detail, Adrenocortical insufficiency is named for its causality. There are two types of this disease: primary, which directly involves the adrenal glands, and secondary, a condition in which the pituitary gland produces inadequate hormones. These can be autoimmune diseases or the result of the development of cancer.

Adrenocortical Insufficiency is in the same class as Addison's disease, evident by the similarity in the grouping of symptoms such as pain in the muscles and gastrointestinal disorders such as nausea, vomiting and diarrhea. Both diseases also cause emaciation, confusion and dehydration. The body is unable to adequately regulate blood concentrations of sodium and potassium which may explain the muscle pain.

Patients suffering this malady frequently have low levels of blood sugar, or hypoglycemia as seen in diabetes. This feature of the illness is of particular concern as it affects the amount of sugar provided to the brain. Levels of blood sugar reaching too low can result in loss of vision, seizures, brain damage and even death.

Female patients suffer from a disproportionately egregious physical effect of the disease owing to the development of characteristics usually associated with masculine development. Early development of body hair and the appearance of facial hair can be very distressing to the female patient and her family. In addition to the reproductive disfigurement, a deeper voice and increased acne may arise. Puberty is reached earlier but usually the female patients do not menstruate.

Adrenal insufficiency diseases lack the increased or hyper-pigmentation common in those suffering from Addison disease, but the loss of salt through the urine is a major factor which must be addressed in treatment. These patients also crave salt in their foods, yet actually display low blood pressure in general, an indication that the sodium has been purged by the body.

Adrenal insufficiency disorders can also result in the patient entering adrenal crisis. Because the adrenal glands produce the glucocorticoids which serve to activate the production and release of substances which control the dilation and constriction of blood vessels, their loss is critical.

Treatment is needed to replace the cortisol and aldosterone which is missing due to the adrenal gland's inability to produce it. A common method is to administer both Florinef and Hydrocortizone.

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