Thursday, March 25, 2010

Ankylosing Spondylitis - New Therapeutic Option

By Neo Tyler

Are you looking for ways on how you can deal with Ankylosing Spondylitis without actually having to go through medications? Or are you looking for remedies or things that you can do to complement your treatments? If you've answered yes to any of the three, then you have come to the right page. In this paper, different natural treatment options for this disorder will be discussed

Some diseases such as psoriasis the rheumatoid arthritis or Ankylosing spondylitis arise since "in the body produces an immune response that is abnormal and exaggerated and that releases certain substances that is responsible for the inflammatory process. With biological therapies act on those substances that origin inflammation or infection"

How a Biological treatment

These are drugs (so called modifiers) clinicians and they have in ordinary seeking to or else recombine successfully blocked the action of Tumor Necrosis Factor.

Tumor Necrosis Factor (TNF):

It is one of the elements involved in maintaining of swollen in patients with AS and is produced by inflammatory cells stimulates coagulation and recruit other leukocytes (white cells) to the site of inflammation. TNF which is one of the cytokines (are diverse and potent chemical messengers secreted by immune-system cells and are the principle tool T cells) immune system's most important is the messenger of a protein (metalloproteinase) is responsible of initiating and magnify the response of patients suffer from inflammation of AS.

TNF is formed in the very immune system cells especially macrophages and T cells when it senses the presence of a pathogen (infectious agent).

The popular potent stimulus to produce TNF is the LPS (found mainly in the cell wall of gram-negative bacteria and other microorganisms).

TNF production is important to defend the body infection but the problem arises when the body creates excessive amounts of TNF being carried by the blood to other parts of the body and its protective role becomes aggressive.

TNF is produced by specific cells macrophages and synoviocytes (for joints) which are cells of the synovial lining. In inflammation of AS the level den be present both in the joint fluid as in serum.

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